Colistin resistance and rapid spread colistin resistance gene: A significant public health challenge worldwide
نویسندگان
چکیده
منابع مشابه
Colistin Resistance in Acinetobacter Lwoffii
Acinetobacter spp. has emerged as a significant hospital pathogen, quickly becoming resistant to commonly used routine drugs. Colistin remains as the only drug of choice for carbapenem resistant Acinetobacter. In our study among 65 strains of Acinetobacter isolated from different clinical samples, 2 strains showed Colistin resistance by Disk diffusion method .It was confirmed by performing mini...
متن کاملDeciphering MCR-2 Colistin Resistance
Antibiotic resistance is a prevalent problem in public health worldwide. In general, the carbapenem β-lactam antibiotics are considered a final resort against lethal infections by multidrug-resistant bacteria. Colistin is a cationic polypeptide antibiotic and acts as the last line of defense for treatment of carbapenem-resistant bacteria. Very recently, a new plasmid-borne colistin resistance g...
متن کاملNew update on molecular determinants of colistin resistance in bacteria
Colistin relates to the polymyxin group of antibiotics. This antibiotic is still used to destroy gram-negative bacteria as a last resort. However, resistance to this antibiotic has been reported and is appearing day by day. Not much information is available on the exact mechanisms of resistance to this antibiotic. Also, not enough information about pharmacokinetics and pharmacodynamics is avail...
متن کاملAquaculture and mcr Colistin Resistance Determinants
We read with great interest the article in mBio regarding the discovery of a third colistin resistance determinant, mcr-3, in plasmid pWJ1 isolated from porcine Escherichia coli in China (1). This discovery and the subsequently reported discovery of a fourth colistin resistance determinant, mcr-4 (2), provide further support for our hypothesis that the mcr determinants (phosphoethanolamine tran...
متن کاملNatural colistin resistance in Edwardsiella tarda.
All of 37 recent human isolates of Edwardsiella tarda were resistant to colistin. All strains were resistant to 6.3 mug of sodium colistimethate per ml; 82% of them were resistant to 100 mug/ml. With 34 Salmonella strains, the average minimal inhibitory concentration (MIC) was 1.6 mug of sodium colistimethate per ml. There was virtually no overlapping of MIC values between both groups of bacter...
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ژورنال
عنوان ژورنال: Advances in Human Biology
سال: 2020
ISSN: 2321-8568
DOI: 10.4103/aihb.aihb_94_19